Slide 2 of 5 of Coagulación sanguínea. VÍA EXTRÍNSECA; 2. Vía Intrínseca; 3. Conversión de la Vías y cascada de la coagulación. Enzimas que actuan en la coagulación.c. Asignatura: .. Al final, las vías intrínse cas y extrínsecas confluyen en una secuencia de etapas en común. hasta. Los factores de la coagulación de la vía extrínseca se activan al producirse el La coagulación también puede activarse por la vía intrínseca al entrar en.

Author: Golabar Tuzahn
Country: Jamaica
Language: English (Spanish)
Genre: Sex
Published (Last): 13 August 2013
Pages: 334
PDF File Size: 7.63 Mb
ePub File Size: 4.33 Mb
ISBN: 415-3-92215-323-3
Downloads: 83862
Price: Free* [*Free Regsitration Required]
Uploader: Daizilkree

Cladistics of the Bryopsidales: Comparative Biochemistry and Physiology B: A total of five species were active in standard clotting test, three of Chlorophyta, one from Phaeophyta and one from Rhodophyta. Agardh, Caulerpa cupressoides West in Vahl C. SPB Academic Publishing bv.

Highly sulfated dermatan sulfates from ascidians. Introduction Thrombosis is a health problem that affects many people in the world. Archivado desde el original el 16 de abril de As anticoagulant time reference 6.

Introduction to Applied Phycology. The coagulation disorders have increased in the last decades and no new substances had been discovered that could regulate this illness.

These localities were chosen due to the relative abundance of the algae. Human plasma was obtained by venous puncture with a disposable syringe, blood was combined with 3. Forty nine seaweed species collected off shore of several localities of Gulf of Mexico and Mexican Caribbean sea were screened in order to detect anticoagulant activity in both intrinsic and extrinsic pathways of clot formation.

An International Journal in Haemostasis and Thrombosis 16 4: We also detected a variation in the anticoagulant potency, a change in the anticoagulant activity related with the intrinsic or extrinsic pathways of coagulation or even the disappearance of the anticoagulant activity in both test of Caulerpa cupressoidesC.

Thrombosis Research 55 3: Occurrence of heparin in the invertebrate Styela plicata Tunicata is restricted to cell layers facing the outside environment.


Alternatively is possible that algal substances acted impeding the polymerization of fibrin for clot formation.

Se concluye que estas especies pueden ser consideradas como una fuente alternativa de nuevos anticoagulantes. It is not common that extracts from algae were active in both tests, in the literature are only few examples as Codium fragile subsp. Remaining algal material was rinsed with tap water and distilled water.

One of the extracts of C. Biochemical and Biophysical Research Communications 2: Finally, sample collected in April of change the anticoagulant activity been extrinseda only in the thrombin time test. These variation has been suggested as been influenced by geographical factors such as climate and locality and has been probed with primary metabolites as lectins by Ingram and Fabregas et al.

Anticoagulant activity in extracts of British marine algae.

Thrombosis is a health problem that affects many people in the world. Our results showed four species with similar activity susceptible of further research for isolation and characterizations of active substances.

An anticoagulant proteoglycan from the marine green alga, Codium pugni-formis. Hemagglutinins in intrineca sea-weeds. The discovery of alternative anticoagulant molecules must be an important task for scientists. Biological activity of extracts from some Mediterranean macrophytes.

Factor de coagulación XI

Journal of Clinical Pathology 6: The extracts could act preventing the conversion of prothrombin to thrombin, also they could act stopping the transformation of fibrinogen to convert it to fibrin o even in the polymerization of this last molecule.

It has been done research in anticoagulant activity of polysaccharides and glycosaminoglycans cadcada diverse sources such as: A fibrinolytic enzyme from a marine green alga, Codium latum.

It is relevant to point out the dependence of anticoagulant potency due to the locality where algae grows, also the date of collection and thus, the climate season is other factor that could influence the synthesis of compounds, particularly extrinesca the brown alga Lobophora variegata we observed the double anticoagulant action in sample collected intrinzeca May ofbut six months later Novembersame specie only was active in the prothrombin time test.


Screening for anticoagulant substances in some marine macroalgae. In the laboratory the material was thawed at room temperature and a fraction of this was preserved in glycerinated formaldehyde for species determination and Voucher organisms, this specimens were kept in our laboratory as internal reference material.

Caulerpa paspaloides Chlorophyta fue activa solamente en el tiempo intrinesca trombina. The research effort has been focused on one genus, forgotten the basic detection of different algae as a potential source of alternative anticoagulant molecules.

Anadyomene stellataCaulerpa cupressoides ChlorophytaLobophora variegata Phaeophyta and Liagora farinosa Rhodophyta. A delay in clot formation less than two minutes was observed in prothrombin time test for this species from Chlorophyta: It has been reported also that brown algae have a potent anticoagulant activity in fucoidans Chevolot et al.

Cada cadena posee una masa molecular de aproximadamente 80 On the quantitative estimation of prothrombin. Other seven species presented a slightly anticoagulant activity. We can concluded that some substances present u the algal extract can act on any of the enzyme or substrate inhibiting the transformation of prothrombin to thrombin or in the activation process of fibrinogen to fibrin.

Journal of Biological Chemistry Anticoagulant and antithrombin activities of oversulfated fucans.

CASCADA DE COAGULACION by mitzy sabrina rodriguez anaya on Prezi

This work deals with the detection of anticoagulant activity in macroalgae from several localities along the Mexican Atlantic coast. This last molecule is a sulfated glicosaminoglycan used in oral therapy for anticoagulant disorders.

Structure of a fucose-branched chondroitin sulfate from sea cucumber. Journal of Molecular Biology 2: Revista de la Sociedad Mexicana de Historia Natural